| Date | Week | Home | Score | Away | Score | |
| 8/28/2021 | 2 | Antigo | 28 | Escanaba (NC) | 42 | |
| 9/3/2021 | 3 | Antigo | 12 | Merrill | 15 | |
| 9/10/2021 | 4 | Ashland | 0 | Antigo | 1 | |
| 9/17/2021 | 5 | Antigo | 0 | Lakeland | 1 | |
| 9/24/2021 | 6 | Rhinelander | 42 | Antigo | 0 | |
| 10/1/2021 | 7 | Antigo | 0 | Medford | 40 | |
| 10/7/2021 | 8 | Antigo | 28 | Hayward/Lac Courte Oreilles | 30 | |
| 10/15/2021 | 9 | Mosinee | 1 | Antigo | 0 | |