| Date | Week | Home | Score | Away | Score | |
| 8/20/2021 | 1 | Lakeland (NC) | 0 | Edgar | 35 | |
| 8/28/2021 | 2 | Stratford (NC) | 9 | Edgar | 8 | |
| 9/3/2021 | 3 | Edgar | 1 | Owen-Withee | 0 | |
| 9/3/2021 | 3 | *Edgar | 36 | *Iola-Scandinavia (NC) | 0 | |
| 9/10/2021 | 4 | Colby | 29 | Edgar | 14 | |
| 9/17/2021 | 5 | Edgar | 42 | Marathon | 0 | |
| 9/24/2021 | 6 | Athens | 0 | Edgar | 1 | |
| 9/24/2021 | 6 | *Hurley (NC) | 22 | *Edgar | 20 | |
| 10/2/2021 | 7 | Edgar | 20 | Auburndale | 6 | |
| 10/8/2021 | 8 | Abbotsford | 16 | Edgar | 30 | |
| 10/15/2021 | 9 | *Benton/Scales Mound IL/Shullsburg (NC) | 0 | *Edgar | 42 | |
| 10/15/2021 | 9 | Thorp | 0 | Edgar | 1 | |