Iola-Scandinavia
Central Wisconsin - Small
| Date | Week | Home | Score | Away | Score | |
| 8/20/2021 | 1 | Iola-Scandinavia | 39 | Marathon (NC) | 14 | |
| 8/27/2021 | 2 | Iola-Scandinavia | 14 | Wittenberg-Birnamwood (NC) | 47 | |
| 9/3/2021 | 3 | *Edgar (NC) | 36 | *Iola-Scandinavia | 0 | |
| 9/3/2021 | 3 | Almond-Bancroft | 0 | Iola-Scandinavia | 1 | |
| 9/10/2021 | 4 | Iola-Scandinavia | 42 | Loyal | 0 | |
| 9/17/2021 | 5 | Assumption | 34 | Iola-Scandinavia | 42 | |
| 9/24/2021 | 6 | Wild Rose | 0 | Iola-Scandinavia | 1 | |
| 10/1/2021 | 7 | Iola-Scandinavia | 12 | Pacelli | 29 | |
| 10/8/2021 | 8 | Iola-Scandinavia | 52 | Rosholt | 0 | |
| 10/15/2021 | 9 | Pittsville | 22 | Iola-Scandinavia | 41 | |
* Denotes the game does not count towards playoff calculation for the team (exhibition only)