| Date | Week | Home | Score | Away | Score | |
| 8/20/2021 | 1 | Laconia | 20 | Wautoma (NC) | 13 | |
| 8/27/2021 | 2 | Markesan (NC) | 14 | Laconia | 8 | |
| 9/3/2021 | 3 | Laconia | 26 | Omro | 7 | |
| 9/10/2021 | 4 | Campbellsport | 30 | Laconia | 0 | |
| 9/17/2021 | 5 | Winnebago Lutheran Academy | 17 | Laconia | 13 | |
| 9/24/2021 | 6 | Laconia | 6 | Mayville | 32 | |
| 10/1/2021 | 7 | North Fond du Lac | 6 | Laconia | 62 | |
| 10/8/2021 | 8 | Lomira | 14 | Laconia | 8 | |
| 10/15/2021 | 9 | Laconia | 14 | St. Mary's Springs | 24 | |