Central Wisconsin - Small
| Date | Week | Home | Score | Away | Score | |
| 8/20/2021 | 1 | Abbotsford (NC) | 47 | Loyal | 12 | |
| 8/27/2021 | 2 | Loyal | 0 | Neillsville/Granton (NC) | 13 | |
| 9/3/2021 | 3 | Rosholt | 8 | Loyal | 26 | |
| 9/10/2021 | 4 | Iola-Scandinavia | 42 | Loyal | 0 | |
| 9/17/2021 | 5 | Loyal | 1 | Wild Rose | 0 | |
| 9/24/2021 | 6 | Loyal | 1 | Almond-Bancroft | 0 | |
| 9/24/2021 | 6 | *Loyal | 16 | *Ladysmith (NC) | 14 | |
| 10/1/2021 | 7 | Pittsville | 26 | Loyal | 32 | |
| 10/8/2021 | 8 | Pacelli | 52 | Loyal | 0 | |
| 10/15/2021 | 9 | Loyal | 14 | Assumption | 49 | |
* Denotes the game does not count towards playoff calculation for the team (exhibition only)