| Week | Date | Home | Score | Away | Score | |
| 5 | 9/18/2025 | Milwaukee Bay View | | Milwaukee Lutheran | | |
| 5 | 9/18/2025 | Milwaukee Madison | 0 | Milwaukee Bay View | 2 | Forfeit |
| 5 | 9/18/2025 | Milwaukee North/Milwaukee WI Conservatory of Lifelong Learning | | Obama SCTE | | |
| 5 | 9/18/2025 | Milwaukee Vincent/Destiny | | Milwaukee Washington/Dr. Howard Fuller Collegiate Academy | | |
| 5 | 9/18/2025 | Medford | | Lakeland | | |
| 5 | 9/18/2025 | Merrill | | Antigo | | |
| 5 | 9/18/2025 | Mosinee | | Wausau East | | |
| 5 | 9/18/2025 | Regis | | Durand-Arkansaw | | |
| 5 | 9/19/2025 | Belleville | | Mineral Point | | |
| 5 | 9/19/2025 | Blair-Taylor | | Cochrane-Fountain City | | |
| 5 | 9/19/2025 | Chilton | | Valders | | |
| 5 | 9/19/2025 | Luxemburg-Casco | | Sheboygan Falls | | |
| 5 | 9/19/2025 | Palmyra-Eagle | | Johnson Creek | | |
| 5 | 9/19/2025 | Stanley-Boyd | | Mondovi | | |
| 5 | 9/19/2025 | Edgewood | | Portage | | |
| 5 | 9/19/2025 | Milwaukee Reagan | | Milwaukee King | | |
| 5 | 9/19/2025 | Milwaukee South | | Milwaukee Riverside/Golda Meir | | |
| 5 | 9/19/2025 | Milwaukee South | | Milwaukee Riverside/Golda Meir | | |
| 5 | 9/19/2025 | Oshkosh North | | Sheboygan South | | |
| 5 | 9/19/2025 | Oshkosh North | | Sheboygan South | | |
| 5 | 9/19/2025 | Kenosha Indian Trail | | Kenosha Tremper | | |
| 5 | 9/19/2025 | Racine Case | | Racine Park | | |
| 5 | 9/19/2025 | Adams-Friendship | | Mauston | | |
| 5 | 9/19/2025 | Adams-Friendship | | Mauston | | |
| 5 | 9/19/2025 | Altoona | | Saint Croix Central | | |
| 5 | 9/19/2025 | Appleton West | | Green Bay Southwest | | |
| 5 | 9/19/2025 | Appleton West | | Green Bay Southwest | | |
| 5 | 9/19/2025 | Aquinas | | Luther | | |
| 5 | 9/19/2025 | Assumption | | Abbotsford | | |
| 5 | 9/19/2025 | Augusta | | Eleva-Strum | | |
| 5 | 9/19/2025 | Augusta | | Eleva-Strum | | |
| 5 | 9/19/2025 | Baldwin-Woodville | | Somerset | | |
| 5 | 9/19/2025 | Baraboo | | Onalaska | | |
| 5 | 9/19/2025 | Barron | | Ashland | | |
| 5 | 9/19/2025 | Bay Port | | Ashwaubenon | | |
| 5 | 9/19/2025 | Bay Port | | Ashwaubenon | | |
| 5 | 9/19/2025 | Belleville | | Mineral Point | | |
| 5 | 9/19/2025 | Beloit Memorial | | Burlington | | |
| 5 | 9/19/2025 | Big Foot | | Columbus | | |
| 5 | 9/19/2025 | Big Foot | | Columbus | | |
| 5 | 9/19/2025 | Black River Falls | | Gale-Ettrick-Trempealeau | | |
| 5 | 9/19/2025 | Blair-Taylor | | Cochrane-Fountain City | | |
| 5 | 9/19/2025 | Bloomer | | Hayward/Lac Courte Oreilles | | |
| 5 | 9/19/2025 | Bonduel | | Marinette | | |
| 5 | 9/19/2025 | Bonduel | | Marinette | | |
| 5 | 9/19/2025 | Boscobel | | Potosi/Cassville | | |
| 5 | 9/19/2025 | Brookfield Academy | | Kenosha St. Joseph Catholic | | |
| 5 | 9/19/2025 | Brookfield Central | | Menomonee Falls | | |
| 5 | 9/19/2025 | Brookwood | | Cashton | | |
| 5 | 9/19/2025 | Brown Deer | | Shoreland Lutheran | | |
| 5 | 9/19/2025 | Brown Deer | | Shoreland Lutheran | | |
| 5 | 9/19/2025 | Catholic Central | | Living Word Lutheran | | |
| 5 | 9/19/2025 | Catholic Memorial | | New Berlin West | | |
| 5 | 9/19/2025 | Cedarburg | | Whitefish Bay | | |
| 5 | 9/19/2025 | Cedarburg | | Whitefish Bay | | |
| 5 | 9/19/2025 | Chilton | | Valders | | |
| 5 | 9/19/2025 | Chippewa Falls | | Rice Lake | | |
| 5 | 9/19/2025 | Clear Lake | | Boyceville | | |
| 5 | 9/19/2025 | Clinton | | Lodi | | |
| 5 | 9/19/2025 | Colby | | Marathon | | |
| 5 | 9/19/2025 | Cuba City | | Southwestern/East Dubuque, IL | | |
| 5 | 9/19/2025 | Cuba City | | Southwestern/East Dubuque, IL | | |
| 5 | 9/19/2025 | Cumberland | | Northwestern | | |
| 5 | 9/19/2025 | D.C. Everest | | Marshfield | | |
| 5 | 9/19/2025 | Darlington | | Benton/Scales Mound (IL)/Shullsburg | | |
| 5 | 9/19/2025 | Darlington | | Benton/Scales Mound (IL)/Shullsburg | | |
| 5 | 9/19/2025 | De Pere | | Green Bay Preble | | |
| 5 | 9/19/2025 | De Pere | | Green Bay Preble | | |
| 5 | 9/19/2025 | DeForest | | Oregon | | |
| 5 | 9/19/2025 | Delavan-Darien | | McFarland | | |
| 5 | 9/19/2025 | East Troy | | Edgerton | | |
| 5 | 9/19/2025 | Eau Claire Memorial | | Eau Claire North | | |
| 5 | 9/19/2025 | Elk Mound | | Osseo-Fairchild | | |
| 5 | 9/19/2025 | Elkhorn Area | | Badger | | |
| 5 | 9/19/2025 | Ellsworth | | Amery | | |
| 5 | 9/19/2025 | Elmwood/Plum City | | Turtle Lake | | |
| 5 | 9/19/2025 | Fall River/Rio | | Markesan | | |
| 5 | 9/19/2025 | Fall River/Rio | | Markesan | | |
| 5 | 9/19/2025 | Fennimore | | Pearl City/Eastland, IL | | |
| 5 | 9/19/2025 | Fennimore | | Abundant Life Christian/Saint Ambrose | | |
| 5 | 9/19/2025 | Fond du Lac | | Kaukauna | | |
| 5 | 9/19/2025 | Franklin | | Oak Creek | | |
| 5 | 9/19/2025 | Freedom | | Fox Valley Lutheran | | |
| 5 | 9/19/2025 | Germantown | | Hamilton | | |
| 5 | 9/19/2025 | Glenwood City | | Colfax | | |
| 5 | 9/19/2025 | Grantsburg | | Cameron | | |
| 5 | 9/19/2025 | Greenfield | | Greendale | | |
| 5 | 9/19/2025 | Hilbert | | Cedar Grove-Belgium | | |
| 5 | 9/19/2025 | Hilbert | | Cedar Grove-Belgium | | |
| 5 | 9/19/2025 | Holmen | | Reedsburg | | |
| 5 | 9/19/2025 | Homestead | | West Bend East | | |
| 5 | 9/19/2025 | Horicon/Hustisford | | Manitowoc Lutheran | | |
| 5 | 9/19/2025 | Horicon/Hustisford | | Manitowoc Lutheran | | |
| 5 | 9/19/2025 | Iola-Scandinavia | | Pacelli | | |
| 5 | 9/19/2025 | Ithaca | | Cashton | | |
| 5 | 9/19/2025 | Janesville Craig | | Madison East | | |
| 5 | 9/19/2025 | Jefferson | | Evansville | | |
| 5 | 9/19/2025 | Kenosha Christian Life | | Dominican | | |
| 5 | 9/19/2025 | Kettle Moraine Lutheran | | Beaver Dam | | |
| 5 | 9/19/2025 | Kewaskum | | Port Washington | | |
| 5 | 9/19/2025 | Kewaskum | | Port Washington | | |
| 5 | 9/19/2025 | Kiel | | Saint Mary Catholic | | |
| 5 | 9/19/2025 | Kiel | | Saint Mary Catholic | | |
| 5 | 9/19/2025 | Kingdom Prep Lutheran | | Pius XI Catholic | | |
| 5 | 9/19/2025 | Kohler/Sheboygan Christian/Sheboygan Area Lutheran | | Brillion | | |
| 5 | 9/19/2025 | La Crosse Logan | | La Crosse Central | | |
| 5 | 9/19/2025 | Lake Country Lutheran | | Saint Thomas More | | |
| 5 | 9/19/2025 | Lancaster | | River Valley | | |
| 5 | 9/19/2025 | Little Chute | | Denmark | | |
| 5 | 9/19/2025 | Lomira | | Omro | | |
| 5 | 9/19/2025 | Lourdes Academy | | Cambria-Friesland | | |
| 5 | 9/19/2025 | Loyal/Greenwood | | Amherst | | |
| 5 | 9/19/2025 | Luxemburg-Casco | | Sheboygan Falls | | |
| 5 | 9/19/2025 | Madison La Follette | | Verona | | |
| 5 | 9/19/2025 | Manawa | | Crivitz | | |
| 5 | 9/19/2025 | Manitowoc Lincoln | | Notre Dame | | |
| 5 | 9/19/2025 | Marshall | | Deerfield | | |
| 5 | 9/19/2025 | Martin Luther | | Racine St. Catherine's | | |
| 5 | 9/19/2025 | Martin Luther | | Racine St. Catherine's | | |
| 5 | 9/19/2025 | Mayville | | Campbellsport | | |
| 5 | 9/19/2025 | Melrose-Mindoro | | Pepin/Alma | | |
| 5 | 9/19/2025 | Menasha | | Green Bay East | | |
| 5 | 9/19/2025 | Middleton | | Janesville Parker | | |
| 5 | 9/19/2025 | Milton | | Monona Grove | | |
| 5 | 9/19/2025 | Milwaukee Bradley Tech/Milwaukee Arts | | Milwaukee Hamilton/Audubon Technology | | |
| 5 | 9/19/2025 | Milwaukee Marshall/Carmen Northwest/Milwaukee Juneau/Milwaukee School of Languages | | Milwaukee Pulaski/Carmen South/Carmen Southeast | | |
| 5 | 9/19/2025 | Milwaukee Marshall/Carmen Northwest/Milwaukee Juneau/Milwaukee School of Languages | | Milwaukee Pulaski/Carmen South/Carmen Southeast | | |
| 5 | 9/19/2025 | Mishicot | | Kewaunee | | |
| 5 | 9/19/2025 | Monroe | | Whitewater | | |
| 5 | 9/19/2025 | Mukwonago | | Kettle Moraine | | |
| 5 | 9/19/2025 | Muskego | | Arrowhead | | |
| 5 | 9/19/2025 | Necedah | | Bangor | | |
| 5 | 9/19/2025 | Neillsville/Granton | | Fall Creek | | |
| 5 | 9/19/2025 | Neillsville/Granton | | Fall Creek | | |
| 5 | 9/19/2025 | New Berlin Eisenhower | | Waukesha South | | |
| 5 | 9/19/2025 | New Glarus | | Brodhead/Juda | | |
| 5 | 9/19/2025 | New Holstein | | Roncalli | | |
| 5 | 9/19/2025 | New Lisbon | | Brookwood | | |
| 5 | 9/19/2025 | New Richmond | | River Falls | | |
| 5 | 9/19/2025 | North Fond du Lac | | Laconia | | |
| 5 | 9/19/2025 | Northland Pines | | Crandon | | |
| 5 | 9/19/2025 | Oconomowoc | | Marquette | | |
| 5 | 9/19/2025 | Oconto Falls | | Clintonville | | |
| 5 | 9/19/2025 | Oconto Falls | | Clintonville | | |
| 5 | 9/19/2025 | Oostburg | | Howards Grove | | |
| 5 | 9/19/2025 | Oostburg | | Howards Grove | | |
| 5 | 9/19/2025 | Osceola | | Prescott | | |
| 5 | 9/19/2025 | Oshkosh North | | Sheboygan South | | |
| 5 | 9/19/2025 | Oshkosh West | | Neenah | | |
| 5 | 9/19/2025 | Oshkosh West | | Neenah | | |
| 5 | 9/19/2025 | Palmyra-Eagle | | Johnson Creek | | |
| 5 | 9/19/2025 | Pardeeville | | Poynette | | |
| 5 | 9/19/2025 | Parkview/Albany | | Dodgeland | | |
| 5 | 9/19/2025 | Peshtigo | | Southern Door | | |
| 5 | 9/19/2025 | Peshtigo | | Southern Door | | |
| 5 | 9/19/2025 | Pittsville | | Edgar | | |
| 5 | 9/19/2025 | Plymouth | | Watertown | | |
| 5 | 9/19/2025 | Prairie du Chien | | Dodgeville | | |
| 5 | 9/19/2025 | Racine Horlick | | Kenosha Bradford | | |
| 5 | 9/19/2025 | Racine Lutheran | | Cudahy | | |
| 5 | 9/19/2025 | Randolph | | Westfield | | |
| 5 | 9/19/2025 | Reedsville | | Random Lake/Ozaukee | | |
| 5 | 9/19/2025 | Rhinelander | | Tomahawk | | |
| 5 | 9/19/2025 | Richland Center | | Platteville | | |
| 5 | 9/19/2025 | Ripon | | Berlin | | |
| 5 | 9/19/2025 | Riverdale | | River Ridge | | |
| 5 | 9/19/2025 | Riverdale | | River Ridge | | |
| 5 | 9/19/2025 | Royall | | Hillsboro | | |
| 5 | 9/19/2025 | Royall | | Hillsboro | | |
| 5 | 9/19/2025 | Saint Croix Falls | | Spooner | | |
| 5 | 9/19/2025 | Saint Francis | | Milwaukee Academy of Science | | |
| 5 | 9/19/2025 | Sauk Prairie | | Lakeside Lutheran | | |
| 5 | 9/19/2025 | Shawano | | Winneconne | | |
| 5 | 9/19/2025 | Shawano | | Winneconne | | |
| 5 | 9/19/2025 | Sheboygan North | | Green Bay West | | |
| 5 | 9/19/2025 | Sheboygan North | | Green Bay West | | |
| 5 | 9/19/2025 | Shiocton | | Coleman | | |
| 5 | 9/19/2025 | Shiocton | | Coleman | | |
| 5 | 9/19/2025 | Slinger | | Nicolet | | |
| 5 | 9/19/2025 | South Milwaukee | | Grafton | | |
| 5 | 9/19/2025 | Sparta | | Tomah | | |
| 5 | 9/19/2025 | Spencer/Columbus Catholic | | Wittenberg-Birnamwood | | |
| 5 | 9/19/2025 | Spring Valley | | Cadott | | |
| 5 | 9/19/2025 | Stanley-Boyd | | Mondovi | | |
| 5 | 9/19/2025 | Stevens Point Area Senior High | | Hudson | | |
| 5 | 9/19/2025 | Stoughton | | Mount Horeb/Barneveld | | |
| 5 | 9/19/2025 | Sturgeon Bay | | Oconto | | |
| 5 | 9/19/2025 | Sun Prairie East | | Sun Prairie West | | |
| 5 | 9/19/2025 | Superior | | Menomonie | | |
| 5 | 9/19/2025 | Turner | | Lake Mills | | |
| 5 | 9/19/2025 | Turner | | Lake Mills | | |
| 5 | 9/19/2025 | Two Rivers | | Wrightstown | | |
| 5 | 9/19/2025 | Union Grove | | Wilmot Union | | |
| 5 | 9/19/2025 | Unity | | Ladysmith | | |
| 5 | 9/19/2025 | Viroqua | | Westby | | |
| 5 | 9/19/2025 | Waterford | | Westosha Central | | |
| 5 | 9/19/2025 | Waterloo | | Cambridge | | |
| 5 | 9/19/2025 | Waukesha North | | West Allis Central | | |
| 5 | 9/19/2025 | Waukesha West | | Pewaukee | | |
| 5 | 9/19/2025 | Waunakee | | Fort Atkinson | | |
| 5 | 9/19/2025 | Waupaca | | Seymour | | |
| 5 | 9/19/2025 | Waupun | | Nekoosa | | |
| 5 | 9/19/2025 | Waupun | | Nekoosa | | |
| 5 | 9/19/2025 | Wausau West | | Wisconsin Rapids Lincoln | | |
| 5 | 9/19/2025 | Wauwatosa East | | Wauwatosa West | | |
| 5 | 9/19/2025 | Wauzeka-Steuben/Seneca | | Pecatonica/Argyle | | |
| 5 | 9/19/2025 | Webster | | Chetek-Weyerhaeuser | | |
| 5 | 9/19/2025 | West Allis Hale | | Brookfield East | | |
| 5 | 9/19/2025 | West Bend West | | Hartford Union | | |
| 5 | 9/19/2025 | West De Pere | | Pulaski | | |
| 5 | 9/19/2025 | West De Pere | | Pulaski | | |
| 5 | 9/19/2025 | West Salem | | Arcadia | | |
| 5 | 9/19/2025 | Weyauwega-Fremont | | Stratford | | |
| 5 | 9/19/2025 | Whitehall | | Independence/Gilmanton | | |
| 5 | 9/19/2025 | Whitehall | | Independence/Gilmanton | | |
| 5 | 9/19/2025 | Whitnall | | Wisconsin Lutheran | | |
| 5 | 9/19/2025 | Winnebago Lutheran | | St. Mary's Springs | | |
| 5 | 9/19/2025 | Wisconsin Dells | | Wautoma | | |
| 5 | 9/19/2025 | Wisconsin Lutheran | | Whitnall | | |
| 5 | 9/19/2025 | Xavier | | New London | | |
| 5 | 9/19/2025 | Middleton | | Janesville Parker | | |
| 5 | 9/19/2025 | Lourdes Academy | | Cambria-Friesland | | |
| 5 | 9/20/2025 | Madison West | | Madison Memorial | | |
| 5 | 9/20/2025 | University School of Milwaukee | | Watertown Luther Prep | | |
| 5 | 9/20/2025 | University School of Milwaukee | | Watertown Luther Prep | | |
| 5 | 9/20/2025 | Black Hawk/Warren, IL | | Iowa-Grant | | |
| 5 | 9/20/2025 | Black Hawk/Warren, IL | | Iowa-Grant | | |