| Date | Week | Home | Score | Away | Score | |
| 8/22/2025 | 1 | Manitowoc Lutheran | 35 | Roncalli (NC) | 0 | |
| 8/28/2025 | 2 | Mishicot (NC) | 12 | Manitowoc Lutheran | 33 | |
| 9/5/2025 | 3 | Manitowoc Lutheran | 50 | Howards Grove | 16 | |
| 9/12/2025 | 4 | Cedar Grove-Belgium | 14 | Manitowoc Lutheran | 47 | |
| 9/19/2025 | 5 | *Manitowoc Lutheran | 51 | *Horicon/Hustisford (NC) | 13 | |
| 9/19/2025 | 5 | Horicon/Hustisford (NC) | | Manitowoc Lutheran | | |
| 9/19/2025 | 5 | Ozaukee | 0 | Manitowoc Lutheran | 1 | |
| 9/25/2025 | 6 | Manitowoc Lutheran | | Random Lake/Ozaukee | | |
| 9/25/2025 | 6 | *Manitowoc Lutheran | 56 | *Random Lake/Ozaukee (NC) | 0 | |
| 9/26/2025 | 6 | Manitowoc Lutheran | 1 | Random Lake | 0 | |
| 10/3/2025 | 7 | Oostburg | | Manitowoc Lutheran | | |
| 10/3/2025 | 7 | Oostburg | 0 | Manitowoc Lutheran | 56 | |
| 10/10/2025 | 8 | Manitowoc Lutheran | | Hilbert | | |
| 10/10/2025 | 8 | Manitowoc Lutheran | 54 | Hilbert | 13 | |
| 10/17/2025 | 9 | Reedsville | 10 | Manitowoc Lutheran | 14 | |