| Date | Week | Home | Score | Away | Score | |
| 8/22/2025 | 1 | South Milwaukee | 7 | Nicolet (NC) | 35 | |
| 8/29/2025 | 2 | Union Grove (NC) | 49 | South Milwaukee | 0 | |
| 9/5/2025 | 3 | Wisconsin Lutheran | 45 | South Milwaukee | 0 | |
| 9/11/2025 | 4 | South Milwaukee | 14 | Whitnall | 48 | |
| 9/19/2025 | 5 | South Milwaukee | 8 | Grafton | 44 | |
| 9/26/2025 | 6 | Greendale | | South Milwaukee | | |
| 9/26/2025 | 6 | Greendale | 42 | South Milwaukee | 7 | |
| 10/3/2025 | 7 | Shorewood/Messmer | 0 | South Milwaukee | 1 | |
| 10/3/2025 | 7 | Kenosha St. Joseph Catholic (NC) | | South Milwaukee | | |
| 10/3/2025 | 7 | *Kenosha St. Joseph Catholic (NC) | 49 | *South Milwaukee | 0 | |
| 10/10/2025 | 8 | Greenfield | | South Milwaukee | | |
| 10/10/2025 | 8 | Greenfield | 42 | South Milwaukee | 15 | |
| 10/17/2025 | 9 | South Milwaukee | | Milwaukee Lutheran | | |
| 10/17/2025 | 9 | South Milwaukee | 30 | Milwaukee Lutheran | 50 | |