| Date | Week | Home | Score | Away | Score | |
| 8/22/2025 | 1 | Whitnall (NC) | 56 | Milwaukee Academy of Science | 20 | |
| 8/29/2025 | 2 | Milwaukee Academy of Science | 0 | Racine St. Catherine's (NC) | 38 | |
| 9/5/2025 | 3 | Kenosha St. Joseph Catholic | 1 | Milwaukee Academy of Science | 0 | |
| 9/12/2025 | 4 | Milwaukee Academy of Science | 12 | Racine Lutheran | 35 | |
| 9/19/2025 | 5 | Saint Francis | | Milwaukee Academy of Science | | |
| 9/26/2025 | 6 | Cudahy | | Milwaukee Academy of Science | | |
| 10/3/2025 | 7 | Milwaukee Academy of Science | | Pius XI Catholic | | |
| 10/9/2025 | 8 | Kingdom Prep Lutheran | | Milwaukee Academy of Science | | |
| 10/17/2025 | 9 | Milwaukee Academy of Science | | Living Word Lutheran | | |