| Date | Week | Home | Score | Away | Score | |
| 8/23/2019 | 1 | Hillsboro (NC) | 6 | Potosi/Cassville | 50 | |
| 8/30/2019 | 2 | Potosi/Cassville | 47 | Royall (NC) | 6 | |
| 9/6/2019 | 3 | Black Hawk/Warren IL | 24 | Potosi/Cassville | 12 | |
| 9/13/2019 | 4 | Potosi/Cassville | 12 | Benton/Scales Mound IL/Shullsburg | 20 | |
| 9/20/2019 | 5 | River Ridge | 21 | Potosi/Cassville | 24 | |
| 9/27/2019 | 6 | Potosi/Cassville | 14 | Pittsville (NC) | 0 | |
| 10/4/2019 | 7 | Potosi/Cassville | 50 | Pecatonica/Argyle | 6 | |
| 10/11/2019 | 8 | Southwestern/East Dubuque, IL | 8 | Potosi/Cassville | 44 | |
| 10/18/2019 | 9 | Boscobel | 0 | Potosi/Cassville | 40 | |