Valley Football Association-West
| Date | Week | Home | Score | Away | Score | |
| 8/20/2021 | 1 | Appleton East (NC) | 7 | Hortonville | 17 | |
| 8/27/2021 | 2 | Hortonville | 32 | West De Pere (NC) | 29 | 2OT |
| 9/3/2021 | 3 | Marshfield | 23 | Hortonville | 13 | |
| 9/10/2021 | 4 | Hortonville | 13 | Stevens Point Area Senior High | 28 | |
| 9/17/2021 | 5 | Appleton West | 23 | Hortonville | 21 | |
| 9/24/2021 | 6 | Wisconsin Rapids Lincoln | 39 | Hortonville | 0 | |
| 10/1/2021 | 7 | *Hortonville | 19 | *Colby (NC) | 13 | |
| 10/1/2021 | 7 | Hortonville | 1 | Wausau East | 0 | |
| 10/8/2021 | 8 | D.C. Everest | 30 | Hortonville | 15 | |
| 10/15/2021 | 9 | Hortonville | 22 | Wausau West | 30 | |
* Denotes the game does not count towards playoff calculation for the team (exhibition only)