| Date | Week | Home | Score | Away | Score | |
| 8/19/2022 | 1 | Milwaukee Bradley Tech/Milw Arts | 7 | Milwaukee Pulaski/Carmen South/Carmen SE (NC) | 60 | |
| 8/25/2022 | 2 | Milwaukee Bradley Tech/Milw Arts | 7 | Milwaukee Reagan | 52 | |
| 9/2/2022 | 3 | Milwaukee Hamilton/Audubon Tech | 56 | Milwaukee Bradley Tech/Milw Arts | 0 | |
| 9/8/2022 | 4 | Milwaukee Bradley Tech/Milw Arts | 0 | Milwaukee Marshall/Carmen NW/Milw Juneau/Milw Languages | 42 | |
| 9/16/2022 | 5 | Milwaukee Riverside/Golda Meir | 55 | Milwaukee Bradley Tech/Milw Arts | 0 | |
| 9/23/2022 | 6 | Milwaukee Bradley Tech/Milw Arts | 0 | Milwaukee Washington/Fuller Collegiate (NC) | 30 | |
| 9/29/2022 | 7 | Milwaukee Bradley Tech/Milw Arts | 7 | Milwaukee Bay View/Milw Lifelong Learning | 28 | |
| 10/7/2022 | 8 | Milwaukee King | 61 | Milwaukee Bradley Tech/Milw Arts | 0 | |
| 10/13/2022 | 9 | Obama SCTE | 8 | Milwaukee Bradley Tech/Milw Arts | 12 | |