| Date | Week | Home | Score | Away | Score | |
| 8/19/2022 | 1 | Milwaukee Riverside/Golda Meir | 0 | Pewaukee (NC) | 45 | |
| 8/25/2022 | 2 | Milwaukee Riverside/Golda Meir | 0 | Milwaukee Hamilton/Audubon Tech | 1 | |
| 9/2/2022 | 3 | Milwaukee Marshall/Carmen NW/Milw Juneau/Milw Languages | 26 | Milwaukee Riverside/Golda Meir | 28 | |
| 9/16/2022 | 5 | Milwaukee Riverside/Golda Meir | 55 | Milwaukee Bradley Tech/Milw Arts | 0 | |
| 9/22/2022 | 6 | Milwaukee Bay View/Milw Lifelong Learning | 0 | Milwaukee Riverside/Golda Meir | 42 | |
| 9/30/2022 | 7 | Milwaukee Riverside/Golda Meir | 0 | Milwaukee King | 27 | |
| 10/6/2022 | 8 | Milwaukee Reagan | 6 | Milwaukee Riverside/Golda Meir | 22 | |
| 10/14/2022 | 9 | Milwaukee Riverside/Golda Meir | 43 | Milwaukee Madison | 0 | |