| Date | Week | Home | Score | Away | Score | |
| 8/26/2022 | 2 | Milwaukee Washington/Fuller Collegiate | 1 | Milwaukee Madison | 0 | |
| 9/1/2022 | 3 | Milwaukee Vincent/Destiny | 36 | Milwaukee Washington/Fuller Collegiate | 6 | |
| 9/9/2022 | 4 | Milwaukee Washington/Fuller Collegiate | 52 | Milwaukee North | 0 | |
| 9/15/2022 | 5 | Milwaukee South | 0 | Milwaukee Washington/Fuller Collegiate | 28 | |
| 9/23/2022 | 6 | Milwaukee Bradley Tech/Milw Arts (NC) | 0 | Milwaukee Washington/Fuller Collegiate | 30 | |
| 9/29/2022 | 7 | Milwaukee Washington/Fuller Collegiate | 2 | Milwaukee Pulaski/Carmen South/Carmen SE | 8 | |
| 10/7/2022 | 8 | Obama SCTE | 0 | Milwaukee Washington/Fuller Collegiate | 28 | |
| 10/14/2022 | 9 | Milwaukee Hamilton/Audubon Tech | 47 | Milwaukee Washington/Fuller Collegiate | 8 | |