| Date | Week | Home | Score | Away | Score | |
| 8/18/2022 | 1 | Badger (NC) | 17 | Greendale | 9 | |
| 8/26/2022 | 2 | Greendale | 55 | Milwaukee Marshall/Carmen NW/Milw Juneau/Milw Languages (NC) | 0 | |
| 9/2/2022 | 3 | Greendale | 35 | Shorewood/Messmer | 2 | |
| 9/9/2022 | 4 | South Milwaukee | 8 | Greendale | 45 | |
| 9/16/2022 | 5 | Cudahy | 0 | Greendale | 79 | |
| 9/23/2022 | 6 | Greendale | 29 | Wisconsin Lutheran | 45 | |
| 9/30/2022 | 7 | Greenfield | 0 | Greendale | 17 | |
| 10/7/2022 | 8 | Greendale | 49 | Whitnall | 27 | |
| 10/14/2022 | 9 | Grafton | 45 | Greendale | 21 | |