Milwaukee Reagan
Milwaukee City (Richardson)
| Date | Week | Home | Score | Away | Score | |
| 8/19/2022 | 1 | Milwaukee Reagan | 6 | Greenfield (NC) | 50 | |
| 8/25/2022 | 2 | Milwaukee Bradley Tech/Milw Arts | 7 | Milwaukee Reagan | 52 | |
| 9/2/2022 | 3 | Milwaukee Reagan | 16 | Milwaukee Bay View/Milw Lifelong Learning | 14 | |
| 9/8/2022 | 4 | Milwaukee King | 55 | Milwaukee Reagan | 6 | |
| 9/16/2022 | 5 | Milwaukee Reagan | 42 | Milwaukee Madison (NC) | 0 | |
| 9/22/2022 | 6 | Milwaukee Reagan | 22 | Milwaukee Hamilton/Audubon Tech | 36 | |
| 9/30/2022 | 7 | Milwaukee Marshall/Carmen NW/Milw Juneau/Milw Languages | 52 | Milwaukee Reagan | 14 | |
| 10/6/2022 | 8 | Milwaukee Reagan | 6 | Milwaukee Riverside/Golda Meir | 22 | |
| 10/13/2022 | 9 | Milwaukee Reagan | 34 | Milwaukee South | 8 | |