| Date | Week | Home | Score | Away | Score | |
| 8/19/2022 | 1 | Beaver Dam (NC) | 0 | Monroe | 39 | |
| 8/26/2022 | 2 | Monroe | 40 | Mount Horeb/Barneveld (NC) | 19 | |
| 9/2/2022 | 3 | McFarland | 0 | Monroe | 36 | |
| 9/9/2022 | 4 | Monroe | 41 | Evansville | 0 | |
| 9/16/2022 | 5 | Monroe | 53 | Jefferson | 15 | |
| 9/23/2022 | 6 | Delavan-Darien | 0 | Monroe | 55 | |
| 9/30/2022 | 7 | Monroe | 52 | Edgerton | 0 | |
| 10/7/2022 | 8 | East Troy | 8 | Monroe | 54 | |
| 10/14/2022 | 9 | Monroe | 47 | Whitewater | 0 | |