| Date | Week | Home | Score | Away | Score | |
| 8/19/2022 | 1 | New Berlin Eisenhower (NC) | 7 | Wisconsin Lutheran | 0 | |
| 8/26/2022 | 2 | Wisconsin Lutheran | 12 | Whitefish Bay (NC) | 28 | |
| 9/2/2022 | 3 | Grafton | 28 | Wisconsin Lutheran | 12 | |
| 9/9/2022 | 4 | Greenfield | 21 | Wisconsin Lutheran | 22 | |
| 9/16/2022 | 5 | Wisconsin Lutheran | 35 | Whitnall | 7 | |
| 9/23/2022 | 6 | Greendale | 29 | Wisconsin Lutheran | 45 | |
| 9/30/2022 | 7 | Wisconsin Lutheran | 57 | Shorewood/Messmer | 26 | |
| 10/7/2022 | 8 | Wisconsin Lutheran | 29 | Milwaukee Academy of Science (NC) | 6 | |
| 10/7/2022 | 8 | Wisconsin Lutheran | 2 | Cudahy | 0 | |
| 10/14/2022 | 9 | South Milwaukee | 27 | Wisconsin Lutheran | 66 | |