| Date | Week | Home | Score | Away | Score | |
| 8/22/2025 | 1 | Pecatonica/Argyle | 0 | New Glarus (NC) | 49 | |
| 8/28/2025 | 2 | Waterloo (NC) | 36 | Pecatonica/Argyle | 0 | |
| 9/5/2025 | 3 | Boscobel | 28 | Pecatonica/Argyle | 50 | |
| 9/12/2025 | 4 | Pecatonica/Argyle | 14 | Iowa-Grant | 51 | |
| 9/19/2025 | 5 | Wauzeka-Steuben/Seneca (NC) | | Pecatonica/Argyle | | |
| 9/19/2025 | 5 | Wauzeka-Steuben/Seneca | 28 | Pecatonica/Argyle | 0 | |
| 9/27/2025 | 6 | Pecatonica/Argyle | | Riverdale (NC) | | |
| 9/27/2025 | 6 | Pecatonica/Argyle | 0 | Riverdale | 31 | |
| 10/4/2025 | 7 | Pecatonica/Argyle | | Black Hawk/Warren, IL (NC) | | |
| 10/4/2025 | 7 | Pecatonica/Argyle | 0 | Black Hawk/Warren, IL | 48 | |
| 10/10/2025 | 8 | Potosi/Cassville | 57 | Pecatonica/Argyle | 0 | |
| 10/10/2025 | 8 | Potosi/Cassville (NC) | | Pecatonica/Argyle | | |
| 10/17/2025 | 9 | Pecatonica/Argyle | | River Ridge (NC) | | |
| 10/17/2025 | 9 | Pecatonica/Argyle | 12 | River Ridge | 54 | |