| Date | Week | Home | Score | Away | Score | |
| 8/21/2025 | 1 | Cashton (NC) | 21 | Wauzeka-Steuben/Seneca | 33 | |
| 8/29/2025 | 2 | Wauzeka-Steuben/Seneca | 44 | Ithaca (NC) | 14 | |
| 9/5/2025 | 3 | Iowa-Grant | 20 | Wauzeka-Steuben/Seneca | 40 | |
| 9/12/2025 | 4 | Wauzeka-Steuben/Seneca | 44 | Riverdale | 15 | |
| 9/19/2025 | 5 | Wauzeka-Steuben/Seneca | | Pecatonica/Argyle (NC) | | |
| 9/19/2025 | 5 | Wauzeka-Steuben/Seneca | 28 | Pecatonica/Argyle | 0 | |
| 9/26/2025 | 6 | Black Hawk/Warren, IL (NC) | | Wauzeka-Steuben/Seneca | | |
| 9/26/2025 | 6 | Black Hawk/Warren, IL | 14 | Wauzeka-Steuben/Seneca | 7 | |
| 10/3/2025 | 7 | Wauzeka-Steuben/Seneca | | Potosi/Cassville (NC) | | |
| 10/3/2025 | 7 | Wauzeka-Steuben/Seneca | 27 | Potosi/Cassville | 33 | |
| 10/10/2025 | 8 | River Ridge (NC) | | Wauzeka-Steuben/Seneca | | |
| 10/10/2025 | 8 | River Ridge | 6 | Wauzeka-Steuben/Seneca | 15 | |
| 10/17/2025 | 9 | Wauzeka-Steuben/Seneca | | Boscobel (NC) | | |
| 10/17/2025 | 9 | Wauzeka-Steuben/Seneca | 66 | Boscobel | 6 | |