| Date | Week | Home | Score | Away | Score | |
| 9/4/2025 | 3 | Milwaukee Vincent/Destiny | 0 | Milwaukee South | 1 | |
| 9/11/2025 | 4 | Milwaukee North/Milwaukee WI Conservatory of Lifelong Learning | 1 | Milwaukee Vincent/Destiny | 0 | |
| 9/18/2025 | 5 | Milwaukee Vincent/Destiny | 18 | Milwaukee Washington/Dr. Howard Fuller Collegiate Academy | 58 | |
| 9/26/2025 | 6 | Milwaukee Vincent/Destiny | | Milwaukee Bradley Tech/Milwaukee Arts | | |
| 9/26/2025 | 6 | Milwaukee Vincent/Destiny | 12 | Milwaukee Bradley Tech/Milwaukee Arts | 36 | |
| 10/2/2025 | 7 | Obama SCTE | | Milwaukee Vincent/Destiny | | |
| 10/2/2025 | 7 | Obama SCTE | 16 | Milwaukee Vincent/Destiny | 18 | |
| 10/9/2025 | 8 | Milwaukee Vincent/Destiny | | Milwaukee Madison | | |
| 10/9/2025 | 8 | Milwaukee Vincent/Destiny | 44 | Milwaukee Madison | 6 | |
| 10/16/2025 | 9 | Milwaukee Bay View | | Milwaukee Vincent/Destiny | | |
| 10/16/2025 | 9 | Milwaukee Bay View | 46 | Milwaukee Vincent/Destiny | 0 | |